So perhaps its no surprise that clinical research appeals to me. The ability to further medical science, treat my kids at the same time, and even be paid to do it (not that it pays much) makes it win-win!
I’ve hinted at it from time to time, but I realized that I haven’t officially written up the Egg Allergy Study that Zax is currently enrolled in. As the study is more than half over, I’ll do it now!
Allergists have long known that eating egg in its baked form (when an egg-allergic patient is able to do so) can reduce the severity of said allergy, or even speed the person in outgrowing it. For the past 18 months, Zax has been in a study looking to measure that phenomenon. The study is comparing eating baked egg to egg oral immunotherapy (OIT) in order to compare the increase in thresholds (tolerance) and the decrease in skin/IgE reactions in both groups.
Note: Please consult with your allergist before attempting to feed baked egg products to someone with an egg allergy!
Zax’s peanut allergy is definitely more severe, but the egg allergy is more limiting. If you think there are peanuts everywhere, you should try baking, or worse yet, buying baked goods without eggs in them! I’d say the only more prevalent major allergens are dairy and soy. (And maybe wheat, but gluten-free has exploded in recent years.) I’ve learned a lot over the years about how to substitute eggs, and I don’t honestly feel that Zax is missing much, but it still would be nice for him to be able to eat a birthday cake that wasn’t made by meonce in a while. Or we could go out to breakfast as a family–yes, that would be nice!
ScreeningIn order to be eligible for the study, Zax had to be capable of eating baked egg. Originally they accepted some entrants who could not and placed them directly into the OIT path, but those slots were filled by the time we found this, so all participants had to be capable of eating baked egg–they were then randomized into either half. Zax had failed a baked egg challenge when he was three, but it had been three years since that happened so we did a challenge with our allergist. It was actually quite a treat to discover that he could finally tolerate baked egg! One dose seemed to be very close to his threshold, but it was still a pass and made us eligible for the study!
To read more of this remarkable journey click here!